|
KMID : 0043320090320091233
|
|
Archives of Pharmacal Research
2009 Volume.32 No. 9 p.1233 ~ p.1236
|
|
|
Two New Acorane Sesquiterpenes from Illicium henryi
|
|
Li Hui Liang
Song Tai-Fa
Zhang Wei-Dong
Shen Yun-Heng
Liu Chun-Mei
Lin Sheng
Xia Xin-Hua
Jin Hui Zi
|
|
|
Abstract
|
|
|
|
Two new acorane sesquiterpenes, 10-hydroxyacoronene (1) and 1β-isopropyl-4β-methyl-9β-hydroxy spiro[4.5]dec-6-en-8-one (2), one new natural product, 4-hydroxy-4, 6-dimethyl-1-tetralone (3), and one known acorane sesquiterpene, acoradiepoxide (4) were isolated from the twigs and leaves of Illicium henryi. The structures of the new compounds were elucidated primarily on the basis of analysis of spectroscopic data. In addition, the inhibitory effect on NO production of these compounds were tested. Compounds 1 and 4 exhibited slight inhibitory effects on NO production with IC50 values of 82.4 μg/mL and 76.5 μg/mL, respectively.
|
|
|
KEYWORD
|
|
|
Illicium henryi, Acorane sesquiterpenes, NO production
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|